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Gore’s CBAS Heparin Surface, the proven heparin bonding technology for lasting thromboresistance, is used in many of our interventional and vascular surgery products. End-point covalent bonding keeps heparin anchored to the device, while the bioactive site remains free to interact with the blood to help prevent clotting.*

  • Proven Heparin Availability: Performance-ready heparin active site1,4*
  • Proven Heparin Bioactivity: Unmatched, persistent ability to take up antithrombin2,4*
  • Proven Lasting Thromboresistance: Improved surface hemocompatibility resulting from heparin availability and bioactivity1,2,3,4*

*See full CBAS Heparin Surface references

CBAS is a trademark of Carmeda AB, a wholly owned subsidiary of W. L. Gore & Associates, Inc.

Featured Gore Products with CBAS Heparin Surface

50% reduction in the risk of graft occlusion compared to standard ePTFE in Critical Limb Ischemia (CLI) patients 1
 

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1. Lindholt JS, Gottschalksen B, Johannesen N, et al. The Scandinavian Propaten® Trial – 1-year patency of PTFE vascular prostheses with heparin-bonded luminal surfaces compared to ordinary pure PTFE vascular prostheses – a randomised clinical controlled multi-centre trial. European Journal of Vascular & Endovascular Surgery 2011;41(5):668-673.

The GORE® TIGRIS® Vascular Stent features Gore's CBAS Heparin Surface, designed to resist thrombus formation, a problem common in both bare metal and drug-eluting stents.
 

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An Investigational Device Exemption (IDE) Clinical Study of the GORE® VIABAHN® Endoprosthesis with Heparin Bioactive Surface** in Japan demonstrated:

  • 88% 12-month primary patency in long, complex SFA lesions (n = 103)1
  • 21.8 cm average lesion length
  • 65.7% chronic total occlusions (CTOs)
  • 84.5% TASC II C&D lesions

 

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** Heparin Bioactive Surface is synonymous with the CBAS Heparin Surface.

1. GORE® VIABAHN® Endoprosthesis Japan IDE Clinical Study demonstrated 12-month primary patency of 92% as defined by evidence of flow with no Target Lesion Revascularization (TLR). The same study demonstrated 88% 12-month primary patency when defined by PSVR of < 2.5 without a TLR.

References

  1. Gore S, Andersson J, Biran R, Underwood C, Riesenfeld J. Heparin surfaces: impact of immobilization chemistry on hemocompatibility and protein adsorption. Journal of Biomedical Materials Research Part B: Applied Biomaterials 2014;102(8):1817-1824.
  2. Begovac PC, Thomson RC, Fisher JL, Hughson A, Gällhagen A. Improvements in GORE-TEX® Vascular Graft performance by Carmeda® BioActive Surface heparin immobilization. European Journal of Vascular & Endovascular Surgery 2003;25(5):432-437.
  3. Carmeda AB. CBAS® Heparin Surface Reference List. Upplands Väsby, Sweden: Carmeda AB; 2017. [Reference List]. http://www.carmeda.se/selected-reading.  Published April 25, 2017. Accessed May 1, 2017.
  4. Data on file: Data from challenging recirculating human blood loop model on file.

Featured Gore Products with CBAS Heparin Surface

50% reduction in the risk of graft occlusion compared to standard ePTFE in Critical Limb Ischemia (CLI) patients 1
 

Learn more >


1. Lindholt JS, Gottschalksen B, Johannesen N, et al. The Scandinavian Propaten® Trial – 1-year patency of PTFE vascular prostheses with heparin-bonded luminal surfaces compared to ordinary pure PTFE vascular prostheses – a randomised clinical controlled multi-centre trial. European Journal of Vascular & Endovascular Surgery 2011;41(5):668-673.

The GORE® TIGRIS® Vascular Stent features Gore's CBAS Heparin Surface, designed to resist thrombus formation, a problem common in both bare metal and drug-eluting stents.
 

Learn more >

An Investigational Device Exemption (IDE) Clinical Study of the GORE® VIABAHN® Endoprosthesis with Heparin Bioactive Surface** in Japan demonstrated:

  • 88% 12-month primary patency in long, complex SFA lesions (n = 103)1
  • 21.8 cm average lesion length
  • 65.7% chronic total occlusions (CTOs)
  • 84.5% TASC II C&D lesions

 

Learn more >


** Heparin Bioactive Surface is synonymous with the CBAS Heparin Surface.

1. GORE® VIABAHN® Endoprosthesis Japan IDE Clinical Study demonstrated 12-month primary patency of 92% as defined by evidence of flow with no Target Lesion Revascularization (TLR). The same study demonstrated 88% 12-month primary patency when defined by PSVR of < 2.5 without a TLR.