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Heparin-bonded ePTFE (Propaten): is it as good as autologous vein for tibial bypass?

Neville et al. 20141

Division of Vascular Surgery, George Washington University, Washington, DC, USA

Primary patency of GORE® PROPATEN® Vascular Graft

1 year 75%



Patient characteristics*

Characteristic N %
Rutherford classification  
3 5 8%
4 17 27%
5 30 48%
6 10 16%
Hypertension 45 73%
Diabetes 29 47%
ESRD 8 13%
Prior bypass 27 44%
Distal anastomosis  
Anterior tibial 15 24%
Posterior tibial 22 35%
Peroneal 21 34%
Dorsalis pedis 4 6%

Study details

  • Retrospective, non-randomized, single-center study
  • Comparing GORE® PROPATEN® Vascular Graft to great saphenous vein
  • Distal vein patch was used at all distal anastomoses
  • There was no statistically significant difference in primary patency or limb salvage between GORE® PROPATEN® Vascular Graft and single-segment great saphenous vein

This experience with heparin-bonded ePTFE grafts for solely tibial artery bypass yielded patency and limb salvage rates that are comparable to intact great saphenous vein. — R. Neville

We believe that a quality saphenous vein remains the ideal conduit for tibial bypass, although HePTFE should be considered when intact ipsilateral or contralateral vein is not available. In our practice, HePTFE has emerged as the choice over arm vein, especially in the ESRD patient who needs upper extremity vein for dialysis access. We would also choose HePTFE over composite short saphenous vein given the increased dissection required and length of conduit. — R. Neville

*GORE® PROPATEN® Vascular Graft group

1. Neville RF, Babrowicz J, Amdur R, Sidawy A. Heparin-bonded ePTFE (Propaten): is it as good as autologous vein for tibial bypass? Italian Journal of Vascular & Endovascular Surgery 2014;21(1)49-56.