GORE® PROPATEN® Vascular Graft, a leading prosthetic vascular graft for lower extremity revascularization, is specifically designed to reduce the risk of acute graft thrombotic failure. With more than a decade of strong performance that includes improving outcomes and reducing reinterventions, this longstanding bypass graft helps deliver both proven clinical and economic value for patients and hospitals.


With more than 10 years of performance, over 600,000 devices implanted, and over 2,000 limbs studied, the GORE® PROPATEN® Vascular Graft is a leading prosthetic bypass graft solution for proven clinical performance and low cumulative cost of care.
GORE® PROPATEN® Vascular Graft
* Overall weighted average primary patency is based on data from 14 peer-reviewed publications meeting pre-determined inclusion criteria.
Proven patency
By substantially reducing acute graft thrombosis within hours after implantation, the CBAS Heparin Surface on the GORE® PROPATEN® Vascular Graft provides clinical benefits that standard ePTFE grafts do not.1

50% reduction in risk of graft occlusion compared to standard ePTFE in critical limb ischemia (CLI) patients.2

Higher primary and secondary patency, and higher limb salvage for below-knee bypass compared to standard ePTFE from 1–3 years.3
Improved clinical outcomes



* Weighted average of GORE® PROPATEN® Vascular Graft data.
** Weighted average of standard ePTFE data.
Measurable value
The GORE® PROPATEN® Vascular Graft is a leading prosthetic bypass graft solution for proven clinical performance and low cumulative cost of care.
Low treatment cost


GORE® PROPATEN® Vascular Graft: long-term value†

Improvement in amputation-free survival

Decrease in revision procedures

Decrease in average costs
† Based on the 3-year published clinical performance and economic model.
Lasting thromboresistance. Proven technology.7
CBAS Heparin Surface
The CBAS Heparin Surface of the GORE® PROPATEN® Vascular Graft consists of a proprietary covalent end-point bond that preserves the active site, thus retaining heparin’s anticoagulant activity.

Heparin availability
Performance-ready heparin active site.4, 6

Heparin bioactivity
Unmatched, persistent ability to take up antithrombin.1, 5

Lasting thromboresistance
Improved surface hemocompatibility resulting from heparin availability and
Sustained heparin bioactivity8
8 years
Explant after 2,939 days
- Femoral to posterior tibial bypass with polyester Linton patch
- Distal anastomosis occluded
4 Years
Explant after 1,553 days (> 4 years)
- Femoropopliteal bypass
In vivo canine carotid artery interposition model
The CBAS Heparin Surface of a 3 mm diameter GORE® PROPATEN® Vascular Graft (top) remains free of thrombus, while the 3 mm diameter control ePTFE graft (bottom) is covered with thrombus in an acute two-hour in vivo canine carotid artery interposition model.
- Begovac PC, Thomson RC, Fisher JL, Hughson A, Gällhagen A. Improvements in GORE-TEX® Vascular Graft performance by Carmeda® BioActive Surface heparin immobilization. European Journal of Vascular & Endovascular Surgery 2003;25(5):432-437.
- Lindholt JS, Gottschalksen B, Johannesen N, et al. The Scandinavian PROPATEN® Trial – 1-year patency of PTFE vascular prostheses with heparin-bonded luminal surfaces compared to ordinary pure PTFE vascular prostheses – a randomized clinical controlled multi-centre trial. European Journal of Vascular & Endovascular Surgery 2011;41(5):668-673.
- GORE® PROPATEN® Vascular Graft. W. L. Gore & Associates Web site. https://www.goremedical.com/propaten/references. Accessed May 15, 2019.
- Gore S, Andersson J, Biran R, Underwood C, Riesenfeld J. Heparin surfaces: impact of immobilization chemistry on hemocompatibility and protein adsorption. Journal of Biomedical Materials Research Part B: Applied Biomaterials 2014;102(8):1817-1824.
- Freeman J, Chen A, Weinberg RJ, Okada T, Chen C, Lin PH. Sustained thromboresistant bioactivity with reduced intimal hyperplasia of heparin-bonded PTFE Propaten Graft in a chronic canine femoral artery bypass model. Annals of Vascular Surgery 2018;49:295-303.
- Biran R, Pond D. Heparin coatings for improving blood compatibility of medical devices. Advanced Drug Delivery Reviews 2017;112:12-23.
- CBAS Heparin Surface. W. L. Gore & Associates Web site. https://www.goremedical.com/cbas/references. Accessed May 3, 2019.
- Biran R. Heparin Activity and Concentration Values from 52 and 96 Month Duration Clinical Explants of the GORE® PROPATEN® Vascular Graft. Flagstaff, AZ: W.L. Gore & Associates, Inc; 2011 [Work plan]. WP104647
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