Will heparin-bonded PTFE replace autologous venous conduits in infrapopliteal bypass?

Peeters et al. 20081

Department of Cardiovascular and Thoracic Surgery, Imelda Hospital, Bonheiden, Belgium

Primary patency of GORE® PROPATEN® Vascular Graft

N=41
1 year 86%
2 years 79%
3 years 75%
N=37
1 year 71%
2 years 60%
3 years 60%

Patient characteristics

Characteristic N %
Rutherford classification  
3 85 56%
4 29 19%
5 39 26%
Vessel runoff  
0 7 5%
1 76 50%
2 43 28%
3 27 18%
Hypertension 88 64%
Diabetes 37 27%
Renal insufficiency 12 9%
BK fem-pop 41 53%
Infrapopliteal 37 47%
TP trunk 11 30%
Anterior tibial 10 27%
Posterior tibial 10 27%
Peroneal 6 16%

Study details

  • Prospective, non-randomized, multi-center study
  • No adjunctive techniques (patches or cuffs) were used in the study
  • The 3-year secondary patency rate for below-knee fem-pop and infrapopliteal bypasses were 80% and 62%, respectively
  • The 3-year limb salvage rate for all CLI patients was 86%*

Propaten® Vascular Graft [GORE® PROPATEN® Vascular Graft] may succeed in bridging the gap between venous and regular PTFE bypass...especially for infrapopliteal bypasses. — P. Peeters

* Limb salvage rates are for both above-knee and below-knee bypasses.

1. Peeters P, Verbist J, Deloose K, Bosiers M.  Will heparin-bonded PTFE replace autologous venous conduits in infrapopliteal bypass?  Italian Journal of Vascular & Endovascular Surgery 2008;15(3):143-148.

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